.....Advertisement.....
.....Advertisement.....

LANL scientists develop 3D tracking microscope

-A A +A
By John Severance

Jim Werner got the idea after attending a conference in Aspen, Colo., back in 2002.
“The conference highlighted two-dimensional views of a single idea and I got the idea we have to start doing this in three-dimensions,” Werner said this week. “I wrote a proposal and got it funded.”
In 2008, Werner and his staff at the Los Alamos National Laboratory came up with the world’s first confocal microscope capable of following the 3D motion of nanometer-sized objects, which earned a 2008 R&D 100 award. That award recognized the top 100 industrial innovations worldwide.
But Werner and his staff were not done yet.
Earlier his month, they developed a 3D tracking microscope to follow three-dimensional movement of individual protein molecules inside live cells.
In an early demonstration, this instrument was used to follow three-dimensional dynamics of key proteins involved in the human allergic response and associated biological signals.
The microscope system simultaneously samples four spots surrounding the molecule under scrutiny and tracks both its spatial and temporal dynamics. To facilitate such tracking, these important signaling molecules are labeled with quantum dots, tiny glowing nanocrystals.
The system enjoys several advantages over other approaches to 3D molecular tracking:


If you subscribe to the newspaper, you receive FREE access to all the exclusive content of the web site! Simply register to receive uninterrupted access to our award-winning and in-depth local online content!

Renew Current or Past Subscription / Register for Online Subscription

If you currently subscribe or have subscribed in the past to the Los Alamos Monitor, then simply find your account number on your mailing label and enter it below.

Click the question mark below to see where your account ID appears on your mailing label.

Newspaper Acct. ID:
info
Street Address:
(exactly as it appears on the label)

If you are a subscriber and you do not know your account ID or don't have a copy of your newspaper available that shows the information on the address label you can click continue below to search for your account.

New Subscription/30 Day Free Trial Account

If you are new to the award winning Los Alamos Monitor and wish to get a subscription or simply gain access to our online content then please enter your ZIP code below and continue to setup your account.

ZIP Code:



Create a limited access account.
Register to participate in community forums, post on the community calendar, blog etc. This registration does not give you full access to read our award winning content, etc.

The Los Alamos Monitor | lacirculation@lamonitor.com | 505-662-4185
256 DP Road, Los Alamos, NM 87544
Office Hours are 8:00 a.m. to 5:00 p.m., Monday through Friday